Raman, Karthik,

An introduction to computational systems biology : systems-level modelling of cellular networks / Karthik Raman. - First edition. - Boca Raton, FL : CRC Press, 2021. - 336 pages : illustrations (black and white) ; 24 cm. - Chapman & Hall/CRC computational biology series . - Chapman & Hall/CRC computational biology series .

Includes bibliographical references and index.

Introduction to modelling Introduction to graph theory Structure of networks Applications of network biology Introduction to dynamic modelling Parameter estimation Discrete dynamic models: Boolean networks Introduction to constraint-based modelling Extending constraint-based approaches Perturbations to metabolic networks Modelling cellular interactions Designing biological circuits Robustness and evolvability of biological systems Epilogue: The Road Ahead

"This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks-a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. The book is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others"--

9781138597327

2020050614


Systems biology.
Biological systems
Molecular biology
Computational biology.--Computer simulation.--Data processing.

570.113 / RAM